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2021 SEASON · WEEK 5

NFL Week 5 2021 ATS results

Favorites went 9-7 against the spread (56.2%) and home teams 7-9 (43.8%). 4 underdogs won outright. The biggest cover: Buffalo Bills beat the number by 20.5 points in BUF @ KC. Games finished 10 over and 6 under the total.

Updated Oct 2, 2026

Week 5 results against the spread

Spread shown as the favorite and points; total = combined points vs the posted line.

MatchupDayFinalSpreadCoveredTotal
Los Angeles Rams@Seattle SeahawksThuLA 26, SEA 17LA -2.5Los Angeles Rams by 6.543 vs 53.5 Under
New York Jets@Atlanta FalconsSunNYJ 20, ATL 27ATL -3Atlanta Falcons by 447 vs 45.5 Over
Philadelphia Eagles@Carolina PanthersSunPHI 21, CAR 18CAR -2.5Philadelphia Eagles by 5.539 vs 46 Under
Green Bay Packers@Cincinnati BengalsSunGB 25, CIN 22GB -2Green Bay Packers by 147 vs 50 Under
New England Patriots@Houston TexansSunNE 25, HOU 22NE -8Houston Texans by 547 vs 39.5 Over
Tennessee Titans@Jacksonville JaguarsSunTEN 37, JAX 19TEN -4Tennessee Titans by 1456 vs 49 Over
Detroit Lions@Minnesota VikingsSunDET 17, MIN 19MIN -10Detroit Lions by 836 vs 49.5 Under
Denver Broncos@Pittsburgh SteelersSunDEN 19, PIT 27DEN -2Pittsburgh Steelers by 1046 vs 40 Over
Miami Dolphins@Tampa Bay BuccaneersSunMIA 17, TB 45TB -11Tampa Bay Buccaneers by 1762 vs 48 Over
New Orleans Saints@Washington CommandersSunNO 33, WAS 22NO -2.5New Orleans Saints by 8.555 vs 43.5 Over
Cleveland Browns@Los Angeles ChargersSunCLE 42, LAC 47LAC -2.5Los Angeles Chargers by 2.589 vs 46.5 Over
Chicago Bears@Las Vegas RaidersSunCHI 20, LV 9LV -5.5Chicago Bears by 16.529 vs 46 Under
San Francisco 49ers@Arizona CardinalsSunSF 10, ARI 17ARI -6Arizona Cardinals by 127 vs 48.5 Under
New York Giants@Dallas CowboysSunNYG 20, DAL 44DAL -7.5Dallas Cowboys by 16.564 vs 53 Over
Buffalo Bills@Kansas City ChiefsSunBUF 38, KC 20KC -2.5Buffalo Bills by 20.558 vs 57 Over
Indianapolis Colts@Baltimore RavensMonIND 25, BAL 31BAL -7.5Indianapolis Colts by 1.556 vs 46.5 Over

Trifecta's five most confident picks that week, graded: Week 5, 2021 recap.

What ATS means

ATS means against the spread. A team covers when it wins by more than the point spread, or loses by fewer points than the spread. A game that lands exactly on the spread is a push and is left out of cover percentages.

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Regular-season games only, using each game's point spread and final score. Cover % = covers / (covers + non-covers). Past performance doesn't guarantee future results. Trifecta is not affiliated with or endorsed by the NFL or any team. Data notes. Ad: SmackTok is a paid partner. Trifecta earns a commission on sign-ups with code TRIFECTA. 21+, select states.