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2021 SEASON · WEEK 4

NFL Week 4 2021 ATS results

Favorites went 8-8 against the spread (50.0%) and home teams 7-9 (43.8%). 6 underdogs won outright. The biggest cover: Buffalo Bills beat the number by 21 points in HOU @ BUF. Games finished 7 over and 9 under the total.

Updated Oct 2, 2026

Week 4 results against the spread

Spread shown as the favorite and points; total = combined points vs the posted line.

MatchupDayFinalSpreadCoveredTotal
Jacksonville Jaguars@Cincinnati BengalsThuJAX 21, CIN 24CIN -7.5Jacksonville Jaguars by 4.545 vs 46 Under
Washington Commanders@Atlanta FalconsSunWAS 34, ATL 30WAS -1Washington Commanders by 364 vs 47.5 Over
Houston Texans@Buffalo BillsSunHOU 0, BUF 40BUF -19Buffalo Bills by 2140 vs 47.5 Under
Detroit Lions@Chicago BearsSunDET 14, CHI 24CHI -3Chicago Bears by 738 vs 42 Under
Carolina Panthers@Dallas CowboysSunCAR 28, DAL 36DAL -4.5Dallas Cowboys by 3.564 vs 51.5 Over
Indianapolis Colts@Miami DolphinsSunIND 27, MIA 17MIA -2.5Indianapolis Colts by 12.544 vs 41.5 Over
Cleveland Browns@Minnesota VikingsSunCLE 14, MIN 7CLE -1Cleveland Browns by 621 vs 52 Under
New York Giants@New Orleans SaintsSunNYG 27, NO 21NO -7.5New York Giants by 13.548 vs 43 Over
Tennessee Titans@New York JetsSunTEN 24, NYJ 27TEN -5.5New York Jets by 8.551 vs 44.5 Over
Kansas City Chiefs@Philadelphia EaglesSunKC 42, PHI 30KC -7.5Kansas City Chiefs by 4.572 vs 53.5 Over
Arizona Cardinals@Los Angeles RamsSunARI 37, LA 20LA -3.5Arizona Cardinals by 20.557 vs 53.5 Over
Seattle Seahawks@San Francisco 49ersSunSEA 28, SF 21SF -2.5Seattle Seahawks by 9.549 vs 52 Under
Baltimore Ravens@Denver BroncosSunBAL 23, DEN 7DEN -1Baltimore Ravens by 1730 vs 44 Under
Pittsburgh Steelers@Green Bay PackersSunPIT 17, GB 27GB -6.5Green Bay Packers by 3.544 vs 45 Under
Tampa Bay Buccaneers@New England PatriotsSunTB 19, NE 17TB -6New England Patriots by 436 vs 49.5 Under
Las Vegas Raiders@Los Angeles ChargersMonLV 14, LAC 28LAC -3Los Angeles Chargers by 1142 vs 52 Under

Trifecta's five most confident picks that week, graded: Week 4, 2021 recap.

What ATS means

ATS means against the spread. A team covers when it wins by more than the point spread, or loses by fewer points than the spread. A game that lands exactly on the spread is a push and is left out of cover percentages.

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Regular-season games only, using each game's point spread and final score. Cover % = covers / (covers + non-covers). Past performance doesn't guarantee future results. Trifecta is not affiliated with or endorsed by the NFL or any team. Data notes. Ad: SmackTok is a paid partner. Trifecta earns a commission on sign-ups with code TRIFECTA. 21+, select states.