Arizona Cardinals at San Francisco 49ers, Levi's Stadium. Sun Sep 27, 4:05 PM ET. The line: SF -7.5; total 48.5. This season the Cardinals are 2-1 against the spread and the 49ers 2-1.
Updated Oct 2, 2026
Arizona Cardinals covered by 1.5 points. The game finished over the total of 48.5.
The last column is the Cardinals on the road and the 49ers at home.
| Team | 2026 | 2025 | Since 2021 | Away / home since 2021 |
|---|---|---|---|---|
| Arizona Cardinals | 2-1 (66.7%) | 6-11 (35.3%) | 46-42 (52.3%) | 28-17 (62.2%) |
| San Francisco 49ers | 2-1 (66.7%) | 11-6 (64.7%) | 47-41 (53.4%) | 23-21 (52.3%) |
| Date | Matchup | Final | Spread | Covered |
|---|---|---|---|---|
| 2026-09-27 | ARI @ SF | ARI 30, SF 36 | SF -7.5 | Arizona Cardinals by 1.5 |
| 2025-11-16 | SF @ ARI | SF 41, ARI 22 | SF -3.5 | San Francisco 49ers by 15.5 |
| 2025-09-21 | ARI @ SF | ARI 15, SF 16 | SF -1.5 | Arizona Cardinals by 0.5 |
| 2025-01-05 | SF @ ARI | SF 24, ARI 47 | ARI -4.5 | Arizona Cardinals by 18.5 |
| 2024-10-06 | ARI @ SF | ARI 24, SF 23 | SF -7 | Arizona Cardinals by 8 |
| 2023-12-17 | SF @ ARI | SF 45, ARI 29 | SF -12.5 | San Francisco 49ers by 3.5 |
ATS means against the spread. A team covers when it wins by more than the point spread, or loses by fewer points than the spread. A game that lands exactly on the spread is a push and is left out of cover percentages.
All Week 3 games · ATS standings · Arizona Cardinals ATS record · San Francisco 49ers ATS record
This page shows history and the posted line only. It is not a prediction.
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Regular-season games only, using each game's point spread and final score. Cover % = covers / (covers + non-covers). Past performance doesn't guarantee future results. Trifecta is not affiliated with or endorsed by the NFL or any team. Data notes. Ad: SmackTok is a paid partner. Trifecta earns a commission on sign-ups with code TRIFECTA. 21+, select states.